HCG 10000 IU
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HCG 10000 IU by BeaCapra — premium research-grade compound verified to ≥99.0% purity via independent HPLC and LC-MS analysis.
Supplied as lyophilized (freeze-dried) powder in vacuum-sealed glass vials. Each batch undergoes rigorous third-party testing to ensure pharmaceutical-grade consistency and stability.
Specifications
- Purity: ≥99.0% (HPLC verified)
- Form: Lyophilized Powder
- Category: Metabolic Research
- Storage: -20°C recommended, protect from light
Quality Assurance
Every BeaCapra product ships with a Certificate of Analysis (COA) documenting purity verification via HPLC and mass spectrometry. Our compounds are synthesized under strict GMP-adjacent protocols and undergo batch-level quality control.
For Research Use Only (RUO). Not intended for human consumption, therapeutic, or diagnostic use.
Research Benefits
- Gonadal Function Research — HCG (Human Chorionic Gonadotropin) is a glycoprotein hormone that activates the LH/CG receptor, making it essential for studying gonadal steroidogenesis and reproductive biology.
- Testosterone Production — HCG stimulates Leydig cell steroidogenesis, providing a tool for studying testosterone biosynthesis pathways and HPG axis regulation.
- Fertility Research — HCG mimics the LH surge, supporting research into ovulation induction, corpus luteum maintenance, and early pregnancy biology.
- Spermatogenesis — In combination with FSH, HCG supports spermatogenic maintenance in hypogonadotropic models.
Mechanism of Action
HCG is a heterodimeric glycoprotein sharing an α-subunit with LH, FSH, and TSH, but with a unique β-subunit that confers LH/CG receptor specificity.
LH/CG Receptor Activation: HCG binds the LH/CG receptor (LHCGR), a G-protein coupled receptor on Leydig cells (testis) and theca/granulosa cells (ovary). Receptor activation stimulates Gs-adenylyl cyclase-cAMP-PKA signaling.
Steroidogenesis: PKA phosphorylates StAR (Steroidogenic Acute Regulatory protein), facilitating cholesterol transport into mitochondria where CYP11A1 initiates steroid hormone synthesis.
Extended Half-Life: HCG's unique β-subunit C-terminal peptide (CTP) with extensive glycosylation extends its plasma half-life to ~24-36 hours, much longer than LH (~20 minutes).
Research Protocol
For research use only.
Reconstitution
Reconstitute lyophilized HCG with provided diluent or bacteriostatic water. Typical: 5,000-10,000 IU/mL.
Research Dosing
- In vivo (murine): 10-100 IU SC for steroidogenesis studies.
- In vitro (Leydig cells): 0.1-10 IU/mL for testosterone production assays.
- Ovulation models: Species-specific dosing per published ovulation induction protocols.
Storage
Lyophilized at 2-8°C or -20°C. Reconstituted at 2-8°C, use within 30 days.
Safety & Handling
Research Use Only.
Known Considerations
- Chronic high-dose HCG can downregulate LH/CG receptors (desensitization), reducing steroidogenic response.
- Potential for ovarian hyperstimulation in female models; monitor follicular development.
- Anti-HCG antibodies may develop with repeated administration, reducing efficacy.
Frequently Asked Questions
- What is HCG?
- Human Chorionic Gonadotropin is a glycoprotein hormone that activates the LH/CG receptor. It shares structural similarity with LH and is widely used in reproductive biology and steroidogenesis research.
- Why does HCG last longer than LH?
- HCG's β-subunit has an extended C-terminal peptide with heavy O-linked glycosylation that slows renal clearance and proteolytic degradation, extending half-life from ~20 minutes (LH) to ~24-36 hours.
- What purity is this product?
- BeaCapra HCG is pharmaceutical-grade with COA documentation provided.
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Customer Reviews
Exceptional purity and fast shipping
Third-party COA verified at 99.1% purity. Arrived in 2 days with proper cold packaging. The documentation included was thorough and professional. Will be ordering again for our lab.
Best supplier I've found
After trying several suppliers, BeaCapra consistently delivers the highest quality compounds. The subscribe & save option is a great value, and their customer support team answered all my questions promptly.
Great product, COA checks out
Ran our own HPLC analysis and confirmed the purity claims. Packaging was secure and discreet. Only minor note — would love to see more size options for some of the newer compounds. Otherwise excellent.
Subscribe & save is the way to go
The 15% discount on subscription makes this the most competitive pricing I've found for research-grade compounds at this purity level. Auto-delivery every 30 days has been seamless. Highly recommend.
Exactly what our research team needed
We've been sourcing from BeaCapra for our university lab and the consistency batch-to-batch is impressive. Every order comes with a COA and the compounds are properly lyophilized. Professional operation all around.
Questions About HCG 10000 IU
General Questions
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